1)"University of life" means learning form daily life rather than getting higher education.
2)"The last straw" means having a little accident or problem, that is happening again and again and so makes a person to lose their patience.
3)"it's on the cards" means something, that destinied to happen.
4)"Until you're blue in the face" means doing something to the end without a success.
5)"Drama queen" designates a person, who's showing off on the public and makes a scandal out of nothing.